Longevity and Stress Resistant Property of 6-Gingerol from Zingiber officinale Roscoe in Caenorhabditis elegans
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چکیده
منابع مشابه
Gingerol Fraction from Zingiber officinale Protects Against Gentamicin-
26 Nephrotoxicity is the main complication of gentamicin (GM) treatment. GM induces 27 renal damage by overproduction of reactive oxygen species and inflammation in 28 proximal tubular cells. Phenolic compounds from ginger, called gingerols, have 29 demonstrated to have antioxidant and anti-inflammatory effects. We investigated if the 30 oral treatment with an enriched solution of gingerols (GF...
متن کاملGingerol fraction from Zingiber officinale protects against gentamicin-induced nephrotoxicity.
Nephrotoxicity is the main complication of gentamicin (GM) treatment. GM induces renal damage by overproduction of reactive oxygen species and inflammation in proximal tubular cells. Phenolic compounds from ginger, called gingerols, have been demonstrated to have antioxidant and anti-inflammatory effects. We investigated if oral treatment with an enriched solution of gingerols (GF) would promot...
متن کاملOptimization of Extraction Conditions for the 6-Shogaol-rich Extract from Ginger (Zingiber officinale Roscoe)
6-Shogaol, a dehydrated form of 6-gingerol, is a minor component in ginger (Zingiber officinale Roscoe) and has recently been reported to have more potent bioactivity than 6-gingerol. Based on the thermal instability of gingerols (their dehydration to corresponding shogaols at high temperature), we aimed to develop an optimal process to maximize the 6-shogaol content during ginger extraction by...
متن کاملLongevity and stress in Caenorhabditis elegans
It has long been understood that many of the same manipulations that increase longevity in Caenorhabditis elegans also increase resistance to various acute stressors, and vice-versa; moreover these findings hold in more complex organisms as well. Nevertheless, the mechanistic relationship between these phenotypes remains unclear, and in many cases the overlap between stress resistance and longe...
متن کاملMedicinal properties of Zingiber officinale Roscoe - A Review
Ginger (Zingiber officinale) belong to Zingiberacae family is one of the famous spices all over the world. It is a perennial creeping plant with long leaves, yellow green flowers and thick tuberous rhizome. This is a type of storage root having pungent taste. Ginger has a long history of medicinal use for more than 2000 years as one of the most versatile medicinal plants having a wide spectrum ...
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ژورنال
عنوان ژورنال: Biomolecules & Therapeutics
سال: 2018
ISSN: 1976-9148,2005-4483
DOI: 10.4062/biomolther.2017.215